USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: H2AZ_HUMAN USC-OGP 2-DE database:  H2AZ_HUMAN H2AZ_HUMAN General information about the entry View entry in simple text format Entry name H2AZ_HUMAN Primary accession number P0C0S5 Secondary accession number(s) P17317 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Histone H2A.Z; Short=H2A/z;. Gene name Name=H2AFZ Synonyms=H2AZ Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1336: pI=5.13; Mw=15865 SPOT OGP-1338: pI=5.68; Mw=15649 Cross-references UniProtKB/Swiss-Prot P0C0S5; H2AZ_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name H2AZ_HUMAN Primary accession number P0C0S5 Secondary accession number(s) B2RD56 P17317 Q6I9U0 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 122) Name and origin of the protein Description RecName: Full=Histone H2A.Z; Short=H2A/z; Gene name Name=H2AFZ Synonyms=H2AZ Encoded on Name=H2AFZ; Synonyms=H2AZ Keywords 3D-structure; Acetylation; Chromosome; Complete proteome; DNA-binding; Isopeptide bond; Methylation; Nucleosome core; Nucleus; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X52317; CAA36553.1; -; mRNA EMBL M37583; AAA35984.1; -; mRNA EMBL L10138; AAC61625.1; -; Genomic_DNA EMBL CR457415; CAG33696.1; -; mRNA EMBL AK315413; BAG37803.1; -; mRNA EMBL AC097460; AAY41013.1; -; Genomic_DNA EMBL CH471057; EAX06118.1; -; Genomic_DNA EMBL BC018002; AAH18002.1; -; mRNA EMBL BC020936; AAH20936.1; -; mRNA EMBL BC103743; AAI03744.1; -; mRNA CCDS CCDS3654.1; -; . PIR A35881; A35881; . RefSeq NP_002097.1; NM_002106.3; . UniGene Hs.119192; -; . PDB 1F66; X-ray; 2.60 A; C/G=1-128 PDB 3WA9; X-ray; 3.07 A; C/G=1-128 PDB 4CAY; X-ray; 1.48 A; A=19-128 PDB 4NFT; X-ray; 2.61 A; A/B/C/D=16-114 PDB 5B31; X-ray; 2.20 A; G=1-128 PDB 5B32; X-ray; 2.35 A; G=1-128 PDB 5B33; X-ray; 2.92 A; C/G=1-128 PDB 5CHL; X-ray; 1.89 A; B=22-113 PDB 5FUG; X-ray; 2.70 A; A/D/G/J=19-128 PDBsum 1F66; -; . PDBsum 3WA9; -; . PDBsum 4CAY; -; . PDBsum 4NFT; -; . PDBsum 5B31; -; . PDBsum 5B32; -; . PDBsum 5B33; -; . PDBsum 5CHL; -; . PDBsum 5FUG; -; . ProteinModelPortal P0C0S5; -; . SMR P0C0S5; -; . BioGrid 109269; 62; . DIP DIP-38593N; -; . IntAct P0C0S5; 4; . MINT MINT-1605675; -; . STRING 9606.ENSP00000296417; -; . iPTMnet P0C0S5; -; . PhosphoSitePlus P0C0S5; -; . SwissPalm P0C0S5; -; . BioMuta H2AFZ; -; . DMDM 83288408; -; . EPD P0C0S5; -; . MaxQB P0C0S5; -; . PaxDb P0C0S5; -; . PeptideAtlas P0C0S5; -; . PRIDE P0C0S5; -; . TopDownProteomics P0C0S5; -; . DNASU 3015; -; . Ensembl ENST00000296417; ENSP00000296417; ENSG00000164032; . GeneID 3015; -; . KEGG hsa:3015; -; . UCSC uc003hvo.2; human; . CTD 3015; -; . DisGeNET 3015; -; . GeneCards H2AFZ; -; . HGNC HGNC:4741; H2AFZ; . HPA CAB022549; -; . HPA HPA057236; -; . MIM 142763; gene; . neXtProt NX_P0C0S5; -; . OpenTargets ENSG00000164032; -; . PharmGKB PA29119; -; . eggNOG KOG1757; Eukaryota; . eggNOG COG5262; LUCA; . GeneTree ENSGT00710000106735; -; . HOGENOM HOG000234652; -; . HOVERGEN HBG009342; -; . InParanoid P0C0S5; -; . KO K11251; -; . OMA LRNKNAN; -; . OrthoDB EOG091G0XGD; -; . PhylomeDB P0C0S5; -; . TreeFam TF354232; -; . Reactome R-HSA-1221632; Meiotic synapsis; . Reactome R-HSA-171306; Packaging Of Telomere Ends; . Reactome R-HSA-201722; Formation of the beta-catenin:TCF transactivating complex; . Reactome R-HSA-212300; PRC2 methylates histones and DNA; . Reactome R-HSA-2299718; Condensation of Prophase Chromosomes; . Reactome R-HSA-2559580; Oxidative Stress Induced Senescence; . Reactome R-HSA-2559582; Senescence-Associated Secretory Phenotype (SASP); . Reactome R-HSA-2559586; DNA Damage/Telomere Stress Induced Senescence; . Reactome R-HSA-3214858; RMTs methylate histone arginines; . Reactome R-HSA-427359; SIRT1 negatively regulates rRNA Expression; . Reactome R-HSA-427389; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; . Reactome R-HSA-427413; NoRC negatively regulates rRNA expression; . Reactome R-HSA-5250924; B-WICH complex positively regulates rRNA expression; . Reactome R-HSA-5334118; DNA methylation; . Reactome R-HSA-5578749; Transcriptional regulation by small RNAs; . Reactome R-HSA-5617472; Activation of anterior HOX genes in hindbrain development during early embryogenesis; . Reactome R-HSA-5625886; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; . Reactome R-HSA-606279; Deposition of new CENPA-containing nucleosomes at the centromere; . Reactome R-HSA-73728; RNA Polymerase I Promoter Opening; . Reactome R-HSA-73777; RNA Polymerase I Chain Elongation; . Reactome R-HSA-912446; Meiotic recombination; . Reactome R-HSA-977225; Amyloid fiber formation; . SIGNOR P0C0S5; -; . ChiTaRS H2AFZ; human; . EvolutionaryTrace P0C0S5; -; . GeneWiki H2AFZ; -; . GenomeRNAi 3015; -; . PMAP-CutDB P0C0S5; -; . PRO PR:P0C0S5; -; . Proteomes UP000005640; Chromosome 4; . Bgee ENSG00000164032; -; . CleanEx HS_H2AFZ; -; . Genevisible P0C0S5; HS; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005719; C:nuclear euchromatin; IDA:UniProtKB; . GO GO:0005720; C:nuclear heterochromatin; IDA:UniProtKB; . GO GO:0000786; C:nucleosome; IEA:UniProtKB-KW; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0031490; F:chromatin DNA binding; IDA:UniProtKB; . GO GO:0031492; F:nucleosomal DNA binding; IDA:UniProtKB; . GO GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB; . GO GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB; . GO GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:UniProtKB; . GO GO:0071392; P:cellular response to estradiol stimulus; IMP:UniProtKB; . GO GO:0006342; P:chromatin silencing; IBA:GO_Central; . GO GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB; . Gene3D 1.10.20.10; -; 1; . InterPro IPR009072; Histone-fold; . InterPro IPR002119; Histone_H2A; . InterPro IPR007125; Histone_H2A/H2B/H3; . InterPro IPR032454; Histone_H2A_C; . InterPro IPR032458; Histone_H2A_CS; . Pfam PF00125; Histone; 1; . Pfam PF16211; Histone_H2A_C; 1; . PRINTS PR00620; HISTONEH2A; . SMART SM00414; H2A; 1; . SUPFAM SSF47113; SSF47113; 1; . PROSITE PS00046; HISTONE_H2A; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]